Novel multi-enzymatic cascade for the conversion of salicin from plant extract into salicylic acid

Novel multi-enzymatic cascade for the conversion of salicin from plant extract into salicylic acid

Novel multi-enzymatic cascade for the conversion of salicin from plant extract into salicylic acid

A novel multi-enzyme cascade converting plant-derived salicin from Salix purpurea bark into salicylic acid was developed during Amandine Moreno’s PhD thesis carried out in collaboration between FARE and Novéal. This original biocatalytic route involves the combination of a b-glucoside, a laccase and a xanthine oxidase. Overcoming the complexity of the plant extract, this green biocatalytic route delivers 95% yield of salicylic acid. It offers a sustainable path to natural preservatives for cosmetics.

Read : Moreno A., Gombault L-N., Cottias A., Rémond C. 2026. Novel Multienzymatic Cascade for the Conversion of Salicin From Plant Extract Into Salicylic Acid. ChemBioChem; 27, e70348. https://doi.org/10.1002/cbic.70348

Contact : Pr Caroline Rémond, caroline.remond@univ-reims.fr

2026-04-21_MORENO A